FLI

Current research projects

Institute for Novel and Emerging Infectious Diseases

  • NADIR The Network of Animal Disease Infectiology research facilities
    National research platform for zoonoses
  • Rodent-borne infectious diseases with zooonotic potential (e.g. Hanta)
  • Prevalence, diagnostics and virulence factors for emerging diseases (Ebola virus, Marburg virus, Crimean-Congo hemorrhagic fever)
  • West Nile-Virus: Studies on the antibody and virus prevalence in Germany and on general factors which modulate the transmission efficiency between humans and birds
  • Threat of a deliberate contamination of food with viruses that are pathogenic to human (hantavirus and hepatitis E virus)
  • Enzymatic rendering for prion-free animal products.
  • Propagation and titration of the scrapie agent from mice and hamsters for the prozess validation of the isolation and purification steps from therapeutic proteins from human plasma
  • The effect of leucodepletion on transmission of BSE by transfusion of sheep blood components
  • GoatBSE: Improvement of goat TSE discriminative diagnosis and susceptibility based assessment of BSE infectivity in goat milk and meat.
  • Detecting bovine spongiform encephalopathy (BSE) infectivity in blood of clinical and preclinical cattle experimentally infected with different BSE strains by blood transfusion to recipient bovines
  • Network of Excellence(NoE) NEUROPRION: Prevention, control and management of prion diseases
  • Transmission of unclassified scrapie survey samples to conventional and transgenic mice
  • Analysis of the distribution and infectivity of two recently discovered atypical High-type (H-type) and Low-type (L-type) strains of the bovine spongiform encephalopathy (BSE) agent in cattle tissues for human consumption.
  • Management of a specified pathogen free small animal husbandry/ generation of transgenic mouse models
  • Support of animal facilities